4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	cAMP-specific 3',5'-cyclic phosphodiesterase 4D Protein (Entity type)	IC50
4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	XIST Gene (Entity type)	0.0059018265
4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMEM230 Gene (Entity type)	0.005404166
4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TFF1 Gene (Entity type)	0.008270933
4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	S100A10 Gene (Entity type)	-0.005160722
4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DHRS2 Gene (Entity type)	0.0069273324
4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NTS Gene (Entity type)	0.005006273
4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Apremilast Compound (Entity type)	0.1742191314697265
4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	STAP2 Gene (Entity type)	-0.0049322397
4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	APBB2 Gene (Entity type)	0.0071113072

4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Protein (Entity type)
IC50

4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
XIST
Gene (Entity type)
0.0059018265

4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TMEM230
Gene (Entity type)
0.005404166

4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TFF1
Gene (Entity type)
0.008270933

4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
S100A10
Gene (Entity type)
-0.005160722

4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DHRS2
Gene (Entity type)
0.0069273324

4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NTS
Gene (Entity type)
0.005006273

4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Apremilast
Compound (Entity type)
0.1742191314697265

4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
STAP2
Gene (Entity type)
-0.0049322397

4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
APBB2
Gene (Entity type)
0.0071113072

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