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Apremilast (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Apremilast's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Apremilast Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EIF5A Gene (Entity type)	0.0037798092
	Apremilast Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CHN1 Gene (Entity type)	0.0036649397
	Apremilast Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SRC Gene (Entity type)	-0.004190838
	Apremilast Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RELB Gene (Entity type)	-0.0033906477
	Apremilast Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MEG3 Gene (Entity type)	-0.0030921453
	Apremilast Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CXCL2 Gene (Entity type)	-0.0032403383
	Apremilast Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	cAMP-specific 3',5'-cyclic phosphodiesterase 4C Protein (Entity type)	IC50
	4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Apremilast Compound (Entity type)	0.1742191314697265
	Apremilast Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NKG7 Gene (Entity type)	-0.0032233694
	Apremilast Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	vismodegib Compound (Entity type)	0.365997314453125

Apremilast
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EIF5A
Gene (Entity type)
0.0037798092

Apremilast
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CHN1
Gene (Entity type)
0.0036649397

Apremilast
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SRC
Gene (Entity type)
-0.004190838

Apremilast
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RELB
Gene (Entity type)
-0.0033906477

Apremilast
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MEG3
Gene (Entity type)
-0.0030921453

Apremilast
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CXCL2
Gene (Entity type)
-0.0032403383

Apremilast
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
cAMP-specific 3',5'-cyclic phosphodiesterase 4C
Protein (Entity type)
IC50

4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Apremilast
Compound (Entity type)
0.1742191314697265

Apremilast
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NKG7
Gene (Entity type)
-0.0032233694

Apremilast
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
vismodegib
Compound (Entity type)
0.365997314453125

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