POLR2L (Gene)

Description: RNA polymerase II, I and III subunit L

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View POLR2L's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with POLR2L.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using POLR2L.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for POLR2L.

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Gene Sets (984)

LINCS L1000 Chem Pert Consensus Sigs (431)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (2)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (550)

A gene set library provided by LINCS

Knowledge Graph Assertions

Source	Relation	Target	Evidence
niguldipine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	POLR2L Gene (Entity type)	-0.0035340213
SD-6-035-A11 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	POLR2L Gene (Entity type)	0.007958324
(R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	POLR2L Gene (Entity type)	-0.0108525455
Valdecoxib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	POLR2L Gene (Entity type)	-0.0043465425
I-606051 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	POLR2L Gene (Entity type)	-0.012006103
SIB-1893 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	POLR2L Gene (Entity type)	0.009738691
AG-592 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	POLR2L Gene (Entity type)	-0.01208406
liranaftate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	POLR2L Gene (Entity type)	0.0051859734
terfenadine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	POLR2L Gene (Entity type)	-0.010157893
Tetrandrine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	POLR2L Gene (Entity type)	-0.005868348