(R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MSMO1 Gene (Entity type)	0.015737165
(R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ACTA2 Gene (Entity type)	-0.011579223
(R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL3 Gene (Entity type)	0.01747844
(R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Kinesin-like protein KIF11 Protein (Entity type)	Ki
(R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GBP1 Gene (Entity type)	-0.010330344
(R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DKK1 Gene (Entity type)	-0.012516905
(R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Potassium voltage-gated channel subfamily H member 2 Protein (Entity type)	IC50
(R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMEM14A Gene (Entity type)	-0.014390536
(R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CDK1 Gene (Entity type)	-0.010837573
(R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SNRNP25 Gene (Entity type)	-0.0101225125

(R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MSMO1
Gene (Entity type)
0.015737165

(R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ACTA2
Gene (Entity type)
-0.011579223

(R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CXCL3
Gene (Entity type)
0.01747844

(R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Kinesin-like protein KIF11
Protein (Entity type)
Ki

(R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GBP1
Gene (Entity type)
-0.010330344

(R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DKK1
Gene (Entity type)
-0.012516905

(R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Potassium voltage-gated channel subfamily H member 2
Protein (Entity type)
IC50

(R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TMEM14A
Gene (Entity type)
-0.014390536

(R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CDK1
Gene (Entity type)
-0.010837573

(R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SNRNP25
Gene (Entity type)
-0.0101225125

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Knowledge Graph Assertions

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