IRF7 (Gene)

Description: interferon regulatory factor 7

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View IRF7's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with IRF7.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using IRF7.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for IRF7.

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Gene Sets (1516)

LINCS L1000 Chem Pert Consensus Sigs (450)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (3)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (1)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (1057)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (5)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
NCS-382 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IRF7 Gene (Entity type)	-0.0055028866
SA-88642 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IRF7 Gene (Entity type)	0.009633131
ritodrine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IRF7 Gene (Entity type)	-0.0035369983
Kawain Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IRF7 Gene (Entity type)	-0.0094552515
MW-SHH-98 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IRF7 Gene (Entity type)	-0.0031445485
Liver_L2_plasmacytoid dendritic cell Anatomy (Entity type)	Has marker gene in liver Knowledge Graph Relation (Entity type)	IRF7 Gene (Entity type)
ruxolitinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IRF7 Gene (Entity type)	-0.003910548
[1,4']Bipiperidinyl-1'-carboxylic acid (S)-4,11-diethyl-4-hydroxy-3,13-dioxo-3,4,12,13-tetrahydro-1H-2-oxa-6,12a-diaza-dibenzo[b,h]fluoren-9-yl ester Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IRF7 Gene (Entity type)	0.0067402623
KFGENEBIN:IRF7-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	IRF7 Gene (Entity type)
Ciglitazone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IRF7 Gene (Entity type)	-0.0030349572