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Ephrin type-A receptor 4 (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Ephrin type-A receptor 4 's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	TAK-901 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Ephrin type-A receptor 4 Protein (Entity type)	Kd
	N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Ephrin type-A receptor 4 Protein (Entity type)	Kd
	Ephrin type-A receptor 4 Protein (Entity type)	Has isoform Knowledge Graph Relation (Entity type)	UNIPROTKB.ISOFORM:P54764-1 CUI Isoform (Entity type)
	(S)-1-((S)-2-((S)-1-((4R,7S,10S,13S,20S,23S,26S,29R)-10-((1H-indol-3-yl)methyl)-4-carbamoyl-20-(3-guanidinopropyl)-23-(4-hydroxybenzyl)-7,13-bis(hydroxymethyl)-26-isopropyl-6,9,12,15,19,22,25,28-octaoxo-1,2-dithia-5,8,11,14,18,21,24,27-octaazacyclotriacontan-29-ylamino)-3-(4-hydroxyphenyl)-1-oxopropan-2-ylcarbamoyl)pyrrolidin-1-yl)-1-oxopropan-2-aminium Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Ephrin type-A receptor 4 Protein (Entity type)	IC50
	PD-173955 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Ephrin type-A receptor 4 Protein (Entity type)	Kd
	3-((S)-2-((S)-1-((4R,7S,10S,13S,20S,23S,26S,29R)-10-((1H-indol-3-yl)methyl)-4-carbamoyl-20-(3-guanidinopropyl)-23-(4-hydroxybenzyl)-7,13-bis(hydroxymethyl)-26-isopropyl-6,9,12,15,19,22,25,28-octaoxo-1,2-dithia-5,8,11,14,18,21,24,27-octaazacyclotriacontan-29-ylamino)-3-(4-hydroxyphenyl)-1-oxopropan-2-ylcarbamoyl)pyrrolidin-1-yl)-3-oxopropan-1-aminium Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Ephrin type-A receptor 4 Protein (Entity type)	IC50
	EXEL-2880/GSK-1363089 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Ephrin type-A receptor 4 Protein (Entity type)	Kd
	3-(4-(5-hydroxy-2-methylphenylamino)pyrimidin-2-ylamino)benzamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Ephrin type-A receptor 4 Protein (Entity type)	Kd
	8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydroxyphenyl-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Ephrin type-A receptor 4 Protein (Entity type)	IC50
	SKI-606 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Ephrin type-A receptor 4 Protein (Entity type)	Kd

TAK-901
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Ephrin type-A receptor 4
Protein (Entity type)
Kd

N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Ephrin type-A receptor 4
Protein (Entity type)
Kd

Ephrin type-A receptor 4
Protein (Entity type)
Has isoform
Knowledge Graph Relation (Entity type)
UNIPROTKB.ISOFORM:P54764-1 CUI
Isoform (Entity type)

(S)-1-((S)-2-((S)-1-((4R,7S,10S,13S,20S,23S,26S,29R)-10-((1H-indol-3-yl)methyl)-4-carbamoyl-20-(3-guanidinopropyl)-23-(4-hydroxybenzyl)-7,13-bis(hydroxymethyl)-26-isopropyl-6,9,12,15,19,22,25,28-octaoxo-1,2-dithia-5,8,11,14,18,21,24,27-octaazacyclotriacontan-29-ylamino)-3-(4-hydroxyphenyl)-1-oxopropan-2-ylcarbamoyl)pyrrolidin-1-yl)-1-oxopropan-2-aminium
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Ephrin type-A receptor 4
Protein (Entity type)
IC50

PD-173955
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Ephrin type-A receptor 4
Protein (Entity type)
Kd

3-((S)-2-((S)-1-((4R,7S,10S,13S,20S,23S,26S,29R)-10-((1H-indol-3-yl)methyl)-4-carbamoyl-20-(3-guanidinopropyl)-23-(4-hydroxybenzyl)-7,13-bis(hydroxymethyl)-26-isopropyl-6,9,12,15,19,22,25,28-octaoxo-1,2-dithia-5,8,11,14,18,21,24,27-octaazacyclotriacontan-29-ylamino)-3-(4-hydroxyphenyl)-1-oxopropan-2-ylcarbamoyl)pyrrolidin-1-yl)-3-oxopropan-1-aminium
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Ephrin type-A receptor 4
Protein (Entity type)
IC50

EXEL-2880/GSK-1363089
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Ephrin type-A receptor 4
Protein (Entity type)
Kd

3-(4-(5-hydroxy-2-methylphenylamino)pyrimidin-2-ylamino)benzamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Ephrin type-A receptor 4
Protein (Entity type)
Kd

8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydroxyphenyl-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Ephrin type-A receptor 4
Protein (Entity type)
IC50

SKI-606
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Ephrin type-A receptor 4
Protein (Entity type)
Kd

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