SKI-606 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SKI-606's neighborhood in the knowledge graph.

Source	Relation	Target	Evidence
SKI-606 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TSC22D3 Gene (Entity type)	0.010516338
SKI-606 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase SIK1 Protein (Entity type)	IC50
SKI-606 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPON1 Gene (Entity type)	-0.0037535713
SKI-606 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Tyrosine-protein kinase Fyn Protein (Entity type)	IC50
SKI-606 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EIF4EBP1 Gene (Entity type)	0.006239674
SKI-606 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SELENOP Gene (Entity type)	-0.004512968
SKI-606 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cyclin-G-associated kinase Protein (Entity type)	Kd
SKI-606 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Tyrosine-protein kinase Lck Protein (Entity type)	Kd
SKI-606 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	PD-407824 Compound (Entity type)	0.5230044722557068
SKI-606 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ACAT2 Gene (Entity type)	0.007238367

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	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

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