Pimavanserin; Nuplazid, 1-(4-fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Pimavanserin; Nuplazid, 1-(4-fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
Pimavanserin; Nuplazid, 1-(4-fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RPS4Y1 Gene (Entity type)	0.0042618345
Pimavanserin; Nuplazid, 1-(4-fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NPY1R Gene (Entity type)	0.004478853
Pimavanserin; Nuplazid, 1-(4-fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPRR3 Gene (Entity type)	-0.005150953
Pimavanserin; Nuplazid, 1-(4-fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Clofibric-acid Compound (Entity type)	0.5035318732261658
Pimavanserin; Nuplazid, 1-(4-fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	5-hydroxytryptamine receptor 2A Protein (Entity type)	IC50
Pimavanserin; Nuplazid, 1-(4-fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EXT1 Gene (Entity type)	0.006106967
Pimavanserin; Nuplazid, 1-(4-fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GNA13 Gene (Entity type)	-0.004445802
Pimavanserin; Nuplazid, 1-(4-fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MARCKS Gene (Entity type)	-0.005222823
3-(5-(4-(1H-imidazol-1-yl)phenyl)-1-(4-carbamoyl-2-methylphenyl)-1H-pyrrol-2-yl)propanoic acid Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Pimavanserin; Nuplazid, 1-(4-fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea Compound (Entity type)	0.4872881174087524
Nilvadipine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Pimavanserin; Nuplazid, 1-(4-fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea Compound (Entity type)	0.3395662307739258