Information PortalData Portal

Data Matrix

Tools & Workflows

Documentation

MARCKS (Gene)

Ensembl Gene ID: ENSG00000277443

Entrez Gene ID: 4082

Description: myristoylated alanine rich protein kinase C substrate

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View MARCKS's neighborhood in the knowledge graph.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with MARCKS.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using MARCKS.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for MARCKS.

Gene Sets (5371)

LINCS L1000 Chem Pert Consensus Sigs (1470)

A gene set library provided by LINCS

Illuminating the Druggable Genome

ARCHS4 IDG Coexp (8)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (1064)

A gene set library provided by LINCS

rummageo gene perturbations (300)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (2081)

A gene set library provided by LINCS

rummageo chemical perturbations (446)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	3-(3-(tert-butylthio)-1-(4-chlorobenzyl)-5-(quinolin-2-ylmethoxy)-1H-indol-2-yl)-2,2-dimethylpropanoic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MARCKS Gene (Entity type)	0.00398207
	Penciclovir Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MARCKS Gene (Entity type)	0.0035348423
	penitrem-a Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MARCKS Gene (Entity type)	-0.0065686693
	CC-401 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MARCKS Gene (Entity type)	0.003184164
	cuneatin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MARCKS Gene (Entity type)	0.009494431
	SGX-523 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MARCKS Gene (Entity type)	0.004532472
	2-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine::2-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine(clothiapine)::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]thiazepine::CHEMBL304902::Clothiapine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MARCKS Gene (Entity type)	0.030697625
	ipatasertib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MARCKS Gene (Entity type)	0.00497432
	fdcyd Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MARCKS Gene (Entity type)	-0.009399931
	HA-14-1 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MARCKS Gene (Entity type)	0.011021549

3-(3-(tert-butylthio)-1-(4-chlorobenzyl)-5-(quinolin-2-ylmethoxy)-1H-indol-2-yl)-2,2-dimethylpropanoic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MARCKS
Gene (Entity type)
0.00398207

Penciclovir
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MARCKS
Gene (Entity type)
0.0035348423

penitrem-a
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MARCKS
Gene (Entity type)
-0.0065686693

CC-401
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MARCKS
Gene (Entity type)
0.003184164

cuneatin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MARCKS
Gene (Entity type)
0.009494431

SGX-523
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MARCKS
Gene (Entity type)
0.004532472

2-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine::2-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine(clothiapine)::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]thiazepine::CHEMBL304902::Clothiapine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MARCKS
Gene (Entity type)
0.030697625

ipatasertib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MARCKS
Gene (Entity type)
0.00497432

fdcyd
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MARCKS
Gene (Entity type)
-0.009399931

HA-14-1
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MARCKS
Gene (Entity type)
0.011021549

DISPLAY PER PAGE

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.