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NPY1R (Gene)

Ensembl Gene ID: ENSG00000164128

Entrez Gene ID: 4886

Description: neuropeptide Y receptor Y1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View NPY1R's neighborhood in the knowledge graph.

Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with NPY1R.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using NPY1R.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for NPY1R.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with NPY1R.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	methoxypyruvic-acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NPY1R Gene (Entity type)	0.025675053
	sericetin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NPY1R Gene (Entity type)	0.009976629
	metrifonate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NPY1R Gene (Entity type)	-0.011386588
	rhizocarpic-acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NPY1R Gene (Entity type)	-0.011184607
	KU-C104133 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NPY1R Gene (Entity type)	0.010785226
	kynurenic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NPY1R Gene (Entity type)	-0.0040663024
	Pimavanserin; Nuplazid, 1-(4-fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NPY1R Gene (Entity type)	0.004478853
	Alfaxalone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NPY1R Gene (Entity type)	0.008529397
	DR-2313 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NPY1R Gene (Entity type)	0.007370281
	Acetic acid 2-[4-methyl-8-(morpholine-4-sulfonyl)-1,3-dioxo-1,3-dihydro-pyrrolo[3,4-c]quinolin-2-yl]-ethyl ester Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NPY1R Gene (Entity type)	0.005539893

methoxypyruvic-acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NPY1R
Gene (Entity type)
0.025675053

sericetin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NPY1R
Gene (Entity type)
0.009976629

metrifonate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NPY1R
Gene (Entity type)
-0.011386588

rhizocarpic-acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NPY1R
Gene (Entity type)
-0.011184607

KU-C104133
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NPY1R
Gene (Entity type)
0.010785226

kynurenic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NPY1R
Gene (Entity type)
-0.0040663024

Pimavanserin; Nuplazid, 1-(4-fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NPY1R
Gene (Entity type)
0.004478853

Alfaxalone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NPY1R
Gene (Entity type)
0.008529397

DR-2313
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NPY1R
Gene (Entity type)
0.007370281

Acetic acid 2-[4-methyl-8-(morpholine-4-sulfonyl)-1,3-dioxo-1,3-dihydro-pyrrolo[3,4-c]quinolin-2-yl]-ethyl ester
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NPY1R
Gene (Entity type)
0.005539893

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