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Danusertib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Danusertib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Danusertib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	H1-2 Gene (Entity type)	0.010149941
	Danusertib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DPYD Gene (Entity type)	-0.0064112237
	Danusertib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KLF2 Gene (Entity type)	-0.0076605207
	Danusertib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BGN Gene (Entity type)	-0.0072160815
	Danusertib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CDH2 Gene (Entity type)	-0.007409662
	Danusertib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EIF5 Gene (Entity type)	-0.0062731
	Danusertib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	4-(9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[e]pyrimido[5,4-c]azepin-2-ylamino)-2-methoxybenzoic acid Compound (Entity type)	0.4712393581867218
	Danusertib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	PF-3758309 Compound (Entity type)	0.4881954193115234
	Danusertib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TFF3 Gene (Entity type)	0.007289783
	Danusertib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	General transcription and DNA repair factor IIH helicase subunit XPD Protein (Entity type)	Kd

Danusertib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
H1-2
Gene (Entity type)
0.010149941

Danusertib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DPYD
Gene (Entity type)
-0.0064112237

Danusertib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KLF2
Gene (Entity type)
-0.0076605207

Danusertib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
BGN
Gene (Entity type)
-0.0072160815

Danusertib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CDH2
Gene (Entity type)
-0.007409662

Danusertib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EIF5
Gene (Entity type)
-0.0062731

Danusertib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
4-(9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[e]pyrimido[5,4-c]azepin-2-ylamino)-2-methoxybenzoic acid
Compound (Entity type)
0.4712393581867218

Danusertib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
PF-3758309
Compound (Entity type)
0.4881954193115234

Danusertib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TFF3
Gene (Entity type)
0.007289783

Danusertib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
General transcription and DNA repair factor IIH helicase subunit XPD
Protein (Entity type)
Kd

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