H1-2 (Gene)

Entrez Gene ID: 3006

Description: H1.2 linker histone, cluster member

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View H1-2's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with H1-2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using H1-2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for H1-2.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with H1-2.

Gene Sets (2893)

ARCHS4 IDG Coexp (5)

A gene set library provided by IDG

rummageo gene perturbations (217)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (4)

A gene set library provided by GTEx

RummaGEO DrugPerturbations 2025 (533)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (1782)

A gene set library provided by LINCS

rummageo chemical perturbations (350)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
pipamperone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	H1-2 Gene (Entity type)	0.009365147
Danusertib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	H1-2 Gene (Entity type)	0.010149941
SA-424380 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	H1-2 Gene (Entity type)	-0.014085957
selinidin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	H1-2 Gene (Entity type)	0.018425357
moroxydine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	H1-2 Gene (Entity type)	-0.021519253
BML-284 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	H1-2 Gene (Entity type)	-0.017303469
VLX-600 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	H1-2 Gene (Entity type)	-0.027099602
(<i>R</i>)-cetirizine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	H1-2 Gene (Entity type)	-0.004390364
Flutrimazole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	H1-2 Gene (Entity type)	-0.0047785477
Metformin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	H1-2 Gene (Entity type)	-0.003375504

pipamperone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
H1-2
Gene (Entity type)
0.009365147

Danusertib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
H1-2
Gene (Entity type)
0.010149941

SA-424380
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
H1-2
Gene (Entity type)
-0.014085957

selinidin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
H1-2
Gene (Entity type)
0.018425357

moroxydine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
H1-2
Gene (Entity type)
-0.021519253

BML-284
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
H1-2
Gene (Entity type)
-0.017303469

VLX-600
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
H1-2
Gene (Entity type)
-0.027099602

(<i>R</i>)-cetirizine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
H1-2
Gene (Entity type)
-0.004390364

Flutrimazole
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
H1-2
Gene (Entity type)
-0.0047785477

Metformin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
H1-2
Gene (Entity type)
-0.003375504

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Knowledge Graph Assertions

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.