Information PortalData Portal

Data Matrix

Tools & Workflows

Documentation

simvastatin (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View simvastatin's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

Report a bug

Data & Metadata

Tools & Use Cases

@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Data & Metadata

Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	simvastatin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IDI1 Gene (Entity type)	0.0053668497
	simvastatin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RCAN1 Gene (Entity type)	-0.0041062194
	simvastatin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GLIPR1 Gene (Entity type)	-0.003628631
	simvastatin Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	3-hydroxy-3-methylglutaryl-coenzyme A reductase Protein (Entity type)	IC50
	simvastatin Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Salmeterol Compound (Entity type)	0.4902530014514923
	simvastatin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DHCR24 Gene (Entity type)	0.005456388
	simvastatin Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Arteriosclerosis Disease or Phenotype (Entity type)
	N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	simvastatin Compound (Entity type)	0.2855071127414703
	simvastatin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DLC1 Gene (Entity type)	-0.0036470697
	simvastatin Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Cerebrovascular accident Disease or Phenotype (Entity type)

simvastatin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IDI1
Gene (Entity type)
0.0053668497

simvastatin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RCAN1
Gene (Entity type)
-0.0041062194

simvastatin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GLIPR1
Gene (Entity type)
-0.003628631

simvastatin
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
3-hydroxy-3-methylglutaryl-coenzyme A reductase
Protein (Entity type)
IC50

simvastatin
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Salmeterol
Compound (Entity type)
0.4902530014514923

simvastatin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DHCR24
Gene (Entity type)
0.005456388

simvastatin
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Arteriosclerosis
Disease or Phenotype (Entity type)

N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
simvastatin
Compound (Entity type)
0.2855071127414703

simvastatin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DLC1
Gene (Entity type)
-0.0036470697

simvastatin
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Cerebrovascular accident
Disease or Phenotype (Entity type)

DISPLAY PER PAGE