simvastatin (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View simvastatin's neighborhood in the knowledge graph.

Source	Relation	Target	Evidence
simvastatin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IDI1 Gene (Entity type)	0.0053668497
simvastatin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RCAN1 Gene (Entity type)	-0.0041062194
simvastatin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GLIPR1 Gene (Entity type)	-0.003628631
simvastatin Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	3-hydroxy-3-methylglutaryl-coenzyme A reductase Protein (Entity type)	IC50
simvastatin Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Salmeterol Compound (Entity type)	0.4902530014514923
simvastatin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DHCR24 Gene (Entity type)	0.005456388
simvastatin Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Arteriosclerosis Disease or Phenotype (Entity type)
N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	simvastatin Compound (Entity type)	0.2855071127414703
simvastatin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DLC1 Gene (Entity type)	-0.0036470697
simvastatin Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Cerebrovascular accident Disease or Phenotype (Entity type)

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	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.