N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MSMO1 Gene (Entity type)	0.024060646
N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SPRR2B Gene (Entity type)	0.016643824
N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CYP1B1 Gene (Entity type)	-0.022629851
N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SMC1A Gene (Entity type)	0.01888032
N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SCGB2A1 Gene (Entity type)	0.015500166
N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KRT14 Gene (Entity type)	0.026824832
N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	INSIG1 Gene (Entity type)	0.023493012
N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	simvastatin Compound (Entity type)	0.2855071127414703
N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TFF3 Gene (Entity type)	0.022653932
N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TGFBI Gene (Entity type)	-0.017924467

N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MSMO1
Gene (Entity type)
0.024060646

N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SPRR2B
Gene (Entity type)
0.016643824

N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CYP1B1
Gene (Entity type)
-0.022629851

N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SMC1A
Gene (Entity type)
0.01888032

N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SCGB2A1
Gene (Entity type)
0.015500166

N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KRT14
Gene (Entity type)
0.026824832

N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
INSIG1
Gene (Entity type)
0.023493012

N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
simvastatin
Compound (Entity type)
0.2855071127414703

N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TFF3
Gene (Entity type)
0.022653932

N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TGFBI
Gene (Entity type)
-0.017924467

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