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darusentan (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View darusentan's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	darusentan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	C3 Gene (Entity type)	-0.0048250775
	darusentan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FGFR3 Gene (Entity type)	-0.0072689406
	darusentan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LEF1 Gene (Entity type)	-0.005092601
	darusentan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HOXA5 Gene (Entity type)	-0.0054936004
	darusentan Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Endothelin-1 receptor Protein (Entity type)	-
	darusentan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AMIGO2 Gene (Entity type)	0.005719043
	darusentan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CCL4 Gene (Entity type)	0.0054033874
	darusentan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RAD23B Gene (Entity type)	0.0045632613
	darusentan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	STEAP1 Gene (Entity type)	-0.0051498855
	darusentan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ALOX5 Gene (Entity type)	0.0044033295

darusentan
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
C3
Gene (Entity type)
-0.0048250775

darusentan
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FGFR3
Gene (Entity type)
-0.0072689406

darusentan
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LEF1
Gene (Entity type)
-0.005092601

darusentan
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HOXA5
Gene (Entity type)
-0.0054936004

darusentan
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Endothelin-1 receptor
Protein (Entity type)
-

darusentan
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AMIGO2
Gene (Entity type)
0.005719043

darusentan
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CCL4
Gene (Entity type)
0.0054033874

darusentan
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RAD23B
Gene (Entity type)
0.0045632613

darusentan
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
STEAP1
Gene (Entity type)
-0.0051498855

darusentan
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ALOX5
Gene (Entity type)
0.0044033295

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