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CHEMBL-374350 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CHEMBL-374350's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	CHEMBL-374350 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HSPA8 Gene (Entity type)	-0.012302629
	SID11114146 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	CHEMBL-374350 Compound (Entity type)	0.6157668828964233
	CHEMBL-374350 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	4-hydroxytamoxifen Compound (Entity type)	0.6328713893890381
	CHEMBL-374350 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	INSIG1 Gene (Entity type)	0.03253727
	CHEMBL-374350 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BAG3 Gene (Entity type)	-0.008860114
	CHEMBL-374350 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DDIT4 Gene (Entity type)	0.017588563
	CHEMBL-374350 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGCR Gene (Entity type)	0.011758983
	CHEMBL-374350 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NPC1 Gene (Entity type)	0.016021933
	clomipramine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	CHEMBL-374350 Compound (Entity type)	0.6867876648902893
	CHEMBL-374350 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KLF10 Gene (Entity type)	-0.008531534

CHEMBL-374350
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HSPA8
Gene (Entity type)
-0.012302629

SID11114146
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
CHEMBL-374350
Compound (Entity type)
0.6157668828964233

CHEMBL-374350
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
4-hydroxytamoxifen
Compound (Entity type)
0.6328713893890381

CHEMBL-374350
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
INSIG1
Gene (Entity type)
0.03253727

CHEMBL-374350
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
BAG3
Gene (Entity type)
-0.008860114

CHEMBL-374350
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DDIT4
Gene (Entity type)
0.017588563

CHEMBL-374350
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HMGCR
Gene (Entity type)
0.011758983

CHEMBL-374350
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NPC1
Gene (Entity type)
0.016021933

clomipramine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
CHEMBL-374350
Compound (Entity type)
0.6867876648902893

CHEMBL-374350
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KLF10
Gene (Entity type)
-0.008531534

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