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clomipramine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View clomipramine's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	clomipramine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Sigma non-opioid intracellular receptor 1 Protein (Entity type)	Ki
	clomipramine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BHLHE40 Gene (Entity type)	0.0066529238
	clomipramine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Sodium-dependent serotonin transporter Protein (Entity type)	Kd
	clomipramine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)-2-naphthamide Compound (Entity type)	0.7074404954910278
	clomipramine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMEM176B Gene (Entity type)	-0.0062550986
	D4476 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	clomipramine Compound (Entity type)	0.4825439155101776
	clomipramine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GADD45B Gene (Entity type)	-0.006608798
	clomipramine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TXNIP Gene (Entity type)	-0.0064341803
	clomipramine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPP1 Gene (Entity type)	-0.011469674
	clomipramine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	CHEMBL-374350 Compound (Entity type)	0.6867876648902893

clomipramine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Sigma non-opioid intracellular receptor 1
Protein (Entity type)
Ki

clomipramine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
BHLHE40
Gene (Entity type)
0.0066529238

clomipramine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Sodium-dependent serotonin transporter
Protein (Entity type)
Kd

clomipramine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)-2-naphthamide
Compound (Entity type)
0.7074404954910278

clomipramine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TMEM176B
Gene (Entity type)
-0.0062550986

D4476
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
clomipramine
Compound (Entity type)
0.4825439155101776

clomipramine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GADD45B
Gene (Entity type)
-0.006608798

clomipramine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TXNIP
Gene (Entity type)
-0.0064341803

clomipramine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SPP1
Gene (Entity type)
-0.011469674

clomipramine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
CHEMBL-374350
Compound (Entity type)
0.6867876648902893

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