Information PortalData Portal

Data Matrix

Tools & Workflows

Documentation

AZD-2171 (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View AZD-2171's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

Report a bug

Data & Metadata

Tools & Use Cases

@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Data & Metadata

Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	AZD-2171 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FKBP11 Gene (Entity type)	-0.0051021245
	AZD-2171 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Platelet-derived growth factor receptor alpha Protein (Entity type)	Kd
	AZD-2171 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EGR3 Gene (Entity type)	-0.0038416735
	AZD-2171 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGCS1 Gene (Entity type)	0.0064491145
	AZD-2171 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CCN1 Gene (Entity type)	-0.0044892547
	AZD-2171 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AKR1C3 Gene (Entity type)	0.005383487
	AZD-2171 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	STE20-like serine/threonine-protein kinase Protein (Entity type)	Ki
	AZD-2171 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CA2 Gene (Entity type)	-0.0046863006
	AZD-2171 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Mast/stem cell growth factor receptor Kit Protein (Entity type)	Kd
	N8-(3-Chloro-4-fluorophenyl)-N2-(1-methylpiperidin-4-yl)-pyrimido[5,4-d]pyrimidine-2,8-diamine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	AZD-2171 Compound (Entity type)	0.4965926706790924

AZD-2171
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FKBP11
Gene (Entity type)
-0.0051021245

AZD-2171
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Platelet-derived growth factor receptor alpha
Protein (Entity type)
Kd

AZD-2171
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EGR3
Gene (Entity type)
-0.0038416735

AZD-2171
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HMGCS1
Gene (Entity type)
0.0064491145

AZD-2171
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CCN1
Gene (Entity type)
-0.0044892547

AZD-2171
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AKR1C3
Gene (Entity type)
0.005383487

AZD-2171
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
STE20-like serine/threonine-protein kinase
Protein (Entity type)
Ki

AZD-2171
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CA2
Gene (Entity type)
-0.0046863006

AZD-2171
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Mast/stem cell growth factor receptor Kit
Protein (Entity type)
Kd

N8-(3-Chloro-4-fluorophenyl)-N2-(1-methylpiperidin-4-yl)-pyrimido[5,4-d]pyrimidine-2,8-diamine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
AZD-2171
Compound (Entity type)
0.4965926706790924

DISPLAY PER PAGE