AZD-2171 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View AZD-2171's neighborhood in the knowledge graph.

Source	Relation	Target	Evidence
AZD-2171 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FKBP11 Gene (Entity type)	-0.0051021245
AZD-2171 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Platelet-derived growth factor receptor alpha Protein (Entity type)	Kd
AZD-2171 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EGR3 Gene (Entity type)	-0.0038416735
AZD-2171 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGCS1 Gene (Entity type)	0.0064491145
AZD-2171 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CCN1 Gene (Entity type)	-0.0044892547
AZD-2171 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AKR1C3 Gene (Entity type)	0.005383487
AZD-2171 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	STE20-like serine/threonine-protein kinase Protein (Entity type)	Ki
AZD-2171 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CA2 Gene (Entity type)	-0.0046863006
AZD-2171 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Mast/stem cell growth factor receptor Kit Protein (Entity type)	Kd
N8-(3-Chloro-4-fluorophenyl)-N2-(1-methylpiperidin-4-yl)-pyrimido[5,4-d]pyrimidine-2,8-diamine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	AZD-2171 Compound (Entity type)	0.4965926706790924

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	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.