FKBP11 (Gene)

Entrez Gene ID: 51303

Description: FKBP prolyl isomerase 11

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View FKBP11's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with FKBP11.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using FKBP11.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for FKBP11.

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Gene Sets (4193)

LINCS L1000 Chem Pert Consensus Sigs (1236)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (6)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (935)

A gene set library provided by LINCS

rummageo gene perturbations (143)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (1600)

A gene set library provided by LINCS

rummageo chemical perturbations (258)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (11)

A gene set library provided by GTEx

HuBMAP ASCT-B (1)

A gene set library provided by HuBMAP

Knowledge Graph Assertions

Source	Relation	Target	Evidence
prednisolone-hemisuccinate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FKBP11 Gene (Entity type)	0.010815822
AZD-2171 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FKBP11 Gene (Entity type)	-0.0051021245
amiloride Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FKBP11 Gene (Entity type)	-0.0032430599
KU-C103875 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FKBP11 Gene (Entity type)	-0.0112073375
Emetine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FKBP11 Gene (Entity type)	-0.01052887
1-isopropyl-6-(6-(4-isopropylpiperazin-1-yl)pyridin-3-yl)-N-((6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl)-1H-indazole-4-carboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FKBP11 Gene (Entity type)	-0.027982103
norethindrone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FKBP11 Gene (Entity type)	0.0037447806
Proguanil Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FKBP11 Gene (Entity type)	-0.004304988
(S)-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FKBP11 Gene (Entity type)	-0.011280677
N-(2-aminophenyl)-4-(((((2R,3S)-9-(dimethylamino)-5-((R)-1-hydroxypropan-2-yl)-3-methyl-6-oxo-2,3,4,5,6,7-hexahydrobenzo[h][1,5]oxazonin-2-yl)methyl)(methyl)amino)methyl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FKBP11 Gene (Entity type)	-0.008936503

prednisolone-hemisuccinate
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FKBP11
Gene (Entity type)
0.010815822

AZD-2171
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FKBP11
Gene (Entity type)
-0.0051021245

amiloride
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FKBP11
Gene (Entity type)
-0.0032430599

KU-C103875
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FKBP11
Gene (Entity type)
-0.0112073375

Emetine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FKBP11
Gene (Entity type)
-0.01052887

1-isopropyl-6-(6-(4-isopropylpiperazin-1-yl)pyridin-3-yl)-N-((6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl)-1H-indazole-4-carboxamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FKBP11
Gene (Entity type)
-0.027982103

norethindrone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FKBP11
Gene (Entity type)
0.0037447806

Proguanil
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FKBP11
Gene (Entity type)
-0.004304988

(S)-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FKBP11
Gene (Entity type)
-0.011280677

N-(2-aminophenyl)-4-(((((2R,3S)-9-(dimethylamino)-5-((R)-1-hydroxypropan-2-yl)-3-methyl-6-oxo-2,3,4,5,6,7-hexahydrobenzo[h][1,5]oxazonin-2-yl)methyl)(methyl)amino)methyl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FKBP11
Gene (Entity type)
-0.008936503

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Knowledge Graph Assertions

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

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