N8-(3-Chloro-4-fluorophenyl)-N2-(1-methylpiperidin-4-yl)-pyrimido[5,4-d]pyrimidine-2,8-diamine (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View N8-(3-Chloro-4-fluorophenyl)-N2-(1-methylpiperidin-4-yl)-pyrimido[5,4-d]pyrimidine-2,8-diamine's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
N8-(3-Chloro-4-fluorophenyl)-N2-(1-methylpiperidin-4-yl)-pyrimido[5,4-d]pyrimidine-2,8-diamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MYBPC1 Gene (Entity type)	-0.0041209925
N8-(3-Chloro-4-fluorophenyl)-N2-(1-methylpiperidin-4-yl)-pyrimido[5,4-d]pyrimidine-2,8-diamine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Metergoline Compound (Entity type)	0.4390147030353546
N8-(3-Chloro-4-fluorophenyl)-N2-(1-methylpiperidin-4-yl)-pyrimido[5,4-d]pyrimidine-2,8-diamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CLU Gene (Entity type)	0.0039299466
N8-(3-Chloro-4-fluorophenyl)-N2-(1-methylpiperidin-4-yl)-pyrimido[5,4-d]pyrimidine-2,8-diamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DUSP6 Gene (Entity type)	-0.005214143
N8-(3-Chloro-4-fluorophenyl)-N2-(1-methylpiperidin-4-yl)-pyrimido[5,4-d]pyrimidine-2,8-diamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GNAS Gene (Entity type)	0.0042130016
N8-(3-Chloro-4-fluorophenyl)-N2-(1-methylpiperidin-4-yl)-pyrimido[5,4-d]pyrimidine-2,8-diamine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	AZD-2171 Compound (Entity type)	0.4965926706790924
N8-(3-Chloro-4-fluorophenyl)-N2-(1-methylpiperidin-4-yl)-pyrimido[5,4-d]pyrimidine-2,8-diamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	COG7 Gene (Entity type)	0.0043720943
N8-(3-Chloro-4-fluorophenyl)-N2-(1-methylpiperidin-4-yl)-pyrimido[5,4-d]pyrimidine-2,8-diamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IER3 Gene (Entity type)	-0.0050357715
N8-(3-Chloro-4-fluorophenyl)-N2-(1-methylpiperidin-4-yl)-pyrimido[5,4-d]pyrimidine-2,8-diamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TNC Gene (Entity type)	-0.005131235
N8-(3-Chloro-4-fluorophenyl)-N2-(1-methylpiperidin-4-yl)-pyrimido[5,4-d]pyrimidine-2,8-diamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PFKFB3 Gene (Entity type)	-0.0041979766