2-[(S)-4-(4-Chloro-phenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-N-(4-hydroxy-phenyl)acetamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-[(S)-4-(4-Chloro-phenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-N-(4-hydroxy-phenyl)acetamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-[(S)-4-(4-Chloro-phenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-N-(4-hydroxy-phenyl)acetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SIK1 Gene (Entity type)	0.011233324
2-[(S)-4-(4-Chloro-phenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-N-(4-hydroxy-phenyl)acetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ZNF91 Gene (Entity type)	-0.010919976
2-[(S)-4-(4-Chloro-phenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-N-(4-hydroxy-phenyl)acetamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl)phenylamino)-5,11-dimethyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one Compound (Entity type)	0.6914514303207397
2-[(S)-4-(4-Chloro-phenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-N-(4-hydroxy-phenyl)acetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EIF1AY Gene (Entity type)	0.00874771
2-[(S)-4-(4-Chloro-phenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-N-(4-hydroxy-phenyl)acetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PLAC8 Gene (Entity type)	-0.0132198585
2-[(S)-4-(4-Chloro-phenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-N-(4-hydroxy-phenyl)acetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GLRX Gene (Entity type)	-0.008212189
2-[(S)-4-(4-Chloro-phenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-N-(4-hydroxy-phenyl)acetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DDX3Y Gene (Entity type)	0.009140034
2-[(S)-4-(4-Chloro-phenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-N-(4-hydroxy-phenyl)acetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PCOLCE Gene (Entity type)	-0.007971208
2-[(S)-4-(4-Chloro-phenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-N-(4-hydroxy-phenyl)acetamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide Compound (Entity type)	0.7090055346488953
(S)-4-(1-(2-(3-chloro-4-methoxyphenethyl)-5-(3,5-dimethylisoxazol-4-yl)-1H-benzo[d]imidazol-1-yl)propan-2-yl)morpholine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-[(S)-4-(4-Chloro-phenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-N-(4-hydroxy-phenyl)acetamide Compound (Entity type)	0.3252418637275696

2-[(S)-4-(4-Chloro-phenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-N-(4-hydroxy-phenyl)acetamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SIK1
Gene (Entity type)
0.011233324

2-[(S)-4-(4-Chloro-phenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-N-(4-hydroxy-phenyl)acetamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ZNF91
Gene (Entity type)
-0.010919976

2-[(S)-4-(4-Chloro-phenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-N-(4-hydroxy-phenyl)acetamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl)phenylamino)-5,11-dimethyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one
Compound (Entity type)
0.6914514303207397

2-[(S)-4-(4-Chloro-phenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-N-(4-hydroxy-phenyl)acetamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EIF1AY
Gene (Entity type)
0.00874771

2-[(S)-4-(4-Chloro-phenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-N-(4-hydroxy-phenyl)acetamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PLAC8
Gene (Entity type)
-0.0132198585

2-[(S)-4-(4-Chloro-phenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-N-(4-hydroxy-phenyl)acetamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GLRX
Gene (Entity type)
-0.008212189

2-[(S)-4-(4-Chloro-phenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-N-(4-hydroxy-phenyl)acetamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DDX3Y
Gene (Entity type)
0.009140034

2-[(S)-4-(4-Chloro-phenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-N-(4-hydroxy-phenyl)acetamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PCOLCE
Gene (Entity type)
-0.007971208

2-[(S)-4-(4-Chloro-phenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-N-(4-hydroxy-phenyl)acetamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide
Compound (Entity type)
0.7090055346488953

(S)-4-(1-(2-(3-chloro-4-methoxyphenethyl)-5-(3,5-dimethylisoxazol-4-yl)-1H-benzo[d]imidazol-1-yl)propan-2-yl)morpholine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-[(S)-4-(4-Chloro-phenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-N-(4-hydroxy-phenyl)acetamide
Compound (Entity type)
0.3252418637275696

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