2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TFF3 Gene (Entity type)	0.007268735
2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ALDH2 Gene (Entity type)	0.0063158977
2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PCCB Gene (Entity type)	0.0062063057
(S)-4-(1-(2-(3-chloro-4-methoxyphenethyl)-5-(3,5-dimethylisoxazol-4-yl)-1H-benzo[d]imidazol-1-yl)propan-2-yl)morpholine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide Compound (Entity type)	0.4301420748233795
2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRT17 Gene (Entity type)	-0.0077618924
2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GSTZ1 Gene (Entity type)	0.0074893665
2-[(S)-4-(4-Chloro-phenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-N-(4-hydroxy-phenyl)acetamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide Compound (Entity type)	0.7090055346488953
2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PYCR1 Gene (Entity type)	-0.010543603
Bromosporine (BSP) Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide Compound (Entity type)	0.7172298431396484
2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	I-BET151 Compound (Entity type)	0.8711305856704712

2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TFF3
Gene (Entity type)
0.007268735

2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ALDH2
Gene (Entity type)
0.0063158977

2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PCCB
Gene (Entity type)
0.0062063057

(S)-4-(1-(2-(3-chloro-4-methoxyphenethyl)-5-(3,5-dimethylisoxazol-4-yl)-1H-benzo[d]imidazol-1-yl)propan-2-yl)morpholine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide
Compound (Entity type)
0.4301420748233795

2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KRT17
Gene (Entity type)
-0.0077618924

2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GSTZ1
Gene (Entity type)
0.0074893665

2-[(S)-4-(4-Chloro-phenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-N-(4-hydroxy-phenyl)acetamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide
Compound (Entity type)
0.7090055346488953

2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PYCR1
Gene (Entity type)
-0.010543603

Bromosporine (BSP)
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide
Compound (Entity type)
0.7172298431396484

2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
I-BET151
Compound (Entity type)
0.8711305856704712

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