N1-[2,2-Dimethyl-1-(1-phenyl-ethylcarbamoyl)-propyl]-N4-hydroxy-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View N*1*-[2,2-Dimethyl-1-(1-phenyl-ethylcarbamoyl)-propyl]-N*4*-hydroxy-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
N1-[2,2-Dimethyl-1-(1-phenyl-ethylcarbamoyl)-propyl]-N4-hydroxy-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Collagenase 3 Protein (Entity type)	IC50
N1-[2,2-Dimethyl-1-(1-phenyl-ethylcarbamoyl)-propyl]-N4-hydroxy-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MLLT11 Gene (Entity type)	0.0106948195
N1-[2,2-Dimethyl-1-(1-phenyl-ethylcarbamoyl)-propyl]-N4-hydroxy-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BNIP3 Gene (Entity type)	0.024393167
N1-[2,2-Dimethyl-1-(1-phenyl-ethylcarbamoyl)-propyl]-N4-hydroxy-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NDRG1 Gene (Entity type)	0.010959892
N1-[2,2-Dimethyl-1-(1-phenyl-ethylcarbamoyl)-propyl]-N4-hydroxy-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AKR1C3 Gene (Entity type)	0.0135276485
N1-[2,2-Dimethyl-1-(1-phenyl-ethylcarbamoyl)-propyl]-N4-hydroxy-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LPIN1 Gene (Entity type)	-0.009556011
N1-[2,2-Dimethyl-1-(1-phenyl-ethylcarbamoyl)-propyl]-N4-hydroxy-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ENO2 Gene (Entity type)	0.016832344
N1-[2,2-Dimethyl-1-(1-phenyl-ethylcarbamoyl)-propyl]-N4-hydroxy-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SQLE Gene (Entity type)	-0.016557246
N1-[2,2-Dimethyl-1-(1-phenyl-ethylcarbamoyl)-propyl]-N4-hydroxy-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SAP30 Gene (Entity type)	0.010694151
N1-[2,2-Dimethyl-1-(1-phenyl-ethylcarbamoyl)-propyl]-N4-hydroxy-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ZNF395 Gene (Entity type)	0.014084528

N*1*-[2,2-Dimethyl-1-(1-phenyl-ethylcarbamoyl)-propyl]-N*4*-hydroxy-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Collagenase 3
Protein (Entity type)
IC50

N*1*-[2,2-Dimethyl-1-(1-phenyl-ethylcarbamoyl)-propyl]-N*4*-hydroxy-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MLLT11
Gene (Entity type)
0.0106948195

N*1*-[2,2-Dimethyl-1-(1-phenyl-ethylcarbamoyl)-propyl]-N*4*-hydroxy-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
BNIP3
Gene (Entity type)
0.024393167

N*1*-[2,2-Dimethyl-1-(1-phenyl-ethylcarbamoyl)-propyl]-N*4*-hydroxy-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NDRG1
Gene (Entity type)
0.010959892

N*1*-[2,2-Dimethyl-1-(1-phenyl-ethylcarbamoyl)-propyl]-N*4*-hydroxy-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AKR1C3
Gene (Entity type)
0.0135276485

N*1*-[2,2-Dimethyl-1-(1-phenyl-ethylcarbamoyl)-propyl]-N*4*-hydroxy-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LPIN1
Gene (Entity type)
-0.009556011

N*1*-[2,2-Dimethyl-1-(1-phenyl-ethylcarbamoyl)-propyl]-N*4*-hydroxy-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ENO2
Gene (Entity type)
0.016832344

N*1*-[2,2-Dimethyl-1-(1-phenyl-ethylcarbamoyl)-propyl]-N*4*-hydroxy-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SQLE
Gene (Entity type)
-0.016557246

N*1*-[2,2-Dimethyl-1-(1-phenyl-ethylcarbamoyl)-propyl]-N*4*-hydroxy-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SAP30
Gene (Entity type)
0.010694151

N*1*-[2,2-Dimethyl-1-(1-phenyl-ethylcarbamoyl)-propyl]-N*4*-hydroxy-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ZNF395
Gene (Entity type)
0.014084528

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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N*1*-[2,2-Dimethyl-1-(1-phenyl-ethylcarbamoyl)-propyl]-N*4*-hydroxy-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide (Compound)

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Knowledge Graph Assertions

Knowledge Graph Assertions

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Consortium

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Resources

Knowledge Graph Assertions

N1-[2,2-Dimethyl-1-(1-phenyl-ethylcarbamoyl)-propyl]-N4-hydroxy-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide (Compound)