5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DNAJB1 Gene (Entity type)	0.022804229
5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IER3 Gene (Entity type)	-0.033062004
5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	JMJD6 Gene (Entity type)	0.016984297
5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PHLDA1 Gene (Entity type)	-0.019435164
5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SERPINE1 Gene (Entity type)	-0.013363885
5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CCL2 Gene (Entity type)	-0.016102
5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HSPD1 Gene (Entity type)	0.020585228
5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EREG Gene (Entity type)	-0.016625538
5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AURKA Gene (Entity type)	0.016010096
17-allyl-17-demethoxygeldanamycin Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide Compound (Entity type)	0.9203543663024902

5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DNAJB1
Gene (Entity type)
0.022804229

5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IER3
Gene (Entity type)
-0.033062004

5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
JMJD6
Gene (Entity type)
0.016984297

5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PHLDA1
Gene (Entity type)
-0.019435164

5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SERPINE1
Gene (Entity type)
-0.013363885

5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CCL2
Gene (Entity type)
-0.016102

5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HSPD1
Gene (Entity type)
0.020585228

5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EREG
Gene (Entity type)
-0.016625538

5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AURKA
Gene (Entity type)
0.016010096

17-allyl-17-demethoxygeldanamycin
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide
Compound (Entity type)
0.9203543663024902

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