(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KRT23 Gene (Entity type)	0.007231284
(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AMIGO2 Gene (Entity type)	0.0066099563
(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	XIST Gene (Entity type)	-0.007047842
methylphenidate Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine Compound (Entity type)	0.4831418395042419
(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BHLHE41 Gene (Entity type)	-0.00792177
(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	A2M Gene (Entity type)	-0.0062096408
(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	methylphenidate Compound (Entity type)	0.4831418395042419
(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EIF1AY Gene (Entity type)	0.0083842985
(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cytochrome P450 2C19 Protein (Entity type)	IC50
(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMOX1 Gene (Entity type)	-0.011327616

(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KRT23
Gene (Entity type)
0.007231284

(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AMIGO2
Gene (Entity type)
0.0066099563

(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
XIST
Gene (Entity type)
-0.007047842

methylphenidate
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine
Compound (Entity type)
0.4831418395042419

(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
BHLHE41
Gene (Entity type)
-0.00792177

(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
A2M
Gene (Entity type)
-0.0062096408

(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
methylphenidate
Compound (Entity type)
0.4831418395042419

(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EIF1AY
Gene (Entity type)
0.0083842985

(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cytochrome P450 2C19
Protein (Entity type)
IC50

(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HMOX1
Gene (Entity type)
-0.011327616

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Knowledge Graph Assertions

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