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methylphenidate (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View methylphenidate's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	methylphenidate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EVI2A Gene (Entity type)	-0.009479664
	methylphenidate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HSPA6 Gene (Entity type)	-0.009864445
	methylphenidate Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Sodium-dependent noradrenaline transporter Protein (Entity type)	IC50
	methylphenidate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SERPING1 Gene (Entity type)	0.012633421
	methylphenidate Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine Compound (Entity type)	0.4831418395042419
	methylphenidate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GOLT1B Gene (Entity type)	-0.00910572
	methylphenidate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SCD Gene (Entity type)	-0.0150802005
	(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	methylphenidate Compound (Entity type)	0.4831418395042419
	methylphenidate Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Narcolepsy Disease or Phenotype (Entity type)
	methylphenidate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SFN Gene (Entity type)	0.010619166

methylphenidate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EVI2A
Gene (Entity type)
-0.009479664

methylphenidate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HSPA6
Gene (Entity type)
-0.009864445

methylphenidate
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Sodium-dependent noradrenaline transporter
Protein (Entity type)
IC50

methylphenidate
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SERPING1
Gene (Entity type)
0.012633421

methylphenidate
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine
Compound (Entity type)
0.4831418395042419

methylphenidate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GOLT1B
Gene (Entity type)
-0.00910572

methylphenidate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SCD
Gene (Entity type)
-0.0150802005

(E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
methylphenidate
Compound (Entity type)
0.4831418395042419

methylphenidate
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Narcolepsy
Disease or Phenotype (Entity type)

methylphenidate
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SFN
Gene (Entity type)
0.010619166

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025