LGR4 (Gene)

Description: leucine rich repeat containing G protein-coupled receptor 4

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View LGR4's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with LGR4.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using LGR4.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for LGR4.

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Gene Sets (1323)

LINCS L1000 Chem Pert Consensus Sigs (624)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (3)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (695)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Urapidil Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LGR4 Gene (Entity type)	-0.0035580015
asymmetrical-dimethylarginine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LGR4 Gene (Entity type)	0.00458145
Lynestrenol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LGR4 Gene (Entity type)	0.021167314
kidney loop of Henle thin ascending limb epithelial cell Anatomy (Entity type)	Has marker gene in kidney Knowledge Graph Relation (Entity type)	LGR4 Gene (Entity type)
proxyfan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LGR4 Gene (Entity type)	0.0076836026
Darapladib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LGR4 Gene (Entity type)	0.005878542
5-Azacitidine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LGR4 Gene (Entity type)	-0.0065784766
hydroxytyrosol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LGR4 Gene (Entity type)	-0.017002355
Pimavanserin; Nuplazid, 1-(4-fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LGR4 Gene (Entity type)	0.004257885
UCL-2077 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LGR4 Gene (Entity type)	-0.009351801