IMPDH2 (Gene)

Description: inosine monophosphate dehydrogenase 2

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View IMPDH2's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with IMPDH2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using IMPDH2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for IMPDH2.

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Gene Sets (1225)

LINCS L1000 Chem Pert Consensus Sigs (556)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (664)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

IDG Drug Targets 2022 (2)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Voxtalisib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IMPDH2 Gene (Entity type)	0.006498243
(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IMPDH2 Gene (Entity type)	0.013449238
AMN-082 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IMPDH2 Gene (Entity type)	0.0075762244
AZD-2014::CHEMBL2336325::US9102670, 1ap Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IMPDH2 Gene (Entity type)	0.009526154
TGF-beta RI kinase inhibitor Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IMPDH2 Gene (Entity type)	0.005311606
apitolisib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IMPDH2 Gene (Entity type)	0.008926796
(S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IMPDH2 Gene (Entity type)	0.011428819
1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IMPDH2 Gene (Entity type)	0.0065061804
5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IMPDH2 Gene (Entity type)	0.019569201
dactolisib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IMPDH2 Gene (Entity type)	0.012947843