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TGF-beta RI kinase inhibitor (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TGF-beta RI kinase inhibitor's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	TGF-beta RI kinase inhibitor Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SRPX Gene (Entity type)	0.0069959736
	TGF-beta RI kinase inhibitor Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TGFBI Gene (Entity type)	-0.009205558
	TGF-beta RI kinase inhibitor Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TSPAN7 Gene (Entity type)	0.0055333357
	TGF-beta RI kinase inhibitor Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EIF5 Gene (Entity type)	0.0064493525
	TGF-beta RI kinase inhibitor Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	INHBA Gene (Entity type)	-0.01128194
	SB-525334 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	TGF-beta RI kinase inhibitor Compound (Entity type)	0.4140298068523407
	4-(2-(4-(2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yloxy)ethyl)morpholine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	TGF-beta RI kinase inhibitor Compound (Entity type)	0.3579794764518738
	TGF-beta RI kinase inhibitor Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CCN2 Gene (Entity type)	-0.0077850437
	TGF-beta RI kinase inhibitor Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KDM5D Gene (Entity type)	-0.0072423466
	TGF-beta RI kinase inhibitor Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	COMP Gene (Entity type)	-0.009618184

TGF-beta RI kinase inhibitor
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SRPX
Gene (Entity type)
0.0069959736

TGF-beta RI kinase inhibitor
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TGFBI
Gene (Entity type)
-0.009205558

TGF-beta RI kinase inhibitor
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TSPAN7
Gene (Entity type)
0.0055333357

TGF-beta RI kinase inhibitor
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EIF5
Gene (Entity type)
0.0064493525

TGF-beta RI kinase inhibitor
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
INHBA
Gene (Entity type)
-0.01128194

SB-525334
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
TGF-beta RI kinase inhibitor
Compound (Entity type)
0.4140298068523407

4-(2-(4-(2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yloxy)ethyl)morpholine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
TGF-beta RI kinase inhibitor
Compound (Entity type)
0.3579794764518738

TGF-beta RI kinase inhibitor
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CCN2
Gene (Entity type)
-0.0077850437

TGF-beta RI kinase inhibitor
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KDM5D
Gene (Entity type)
-0.0072423466

TGF-beta RI kinase inhibitor
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
COMP
Gene (Entity type)
-0.009618184

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