IRF8 (Gene)

Description: interferon regulatory factor 8

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View IRF8's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with IRF8.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using IRF8.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for IRF8.

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Gene Sets (1027)

LINCS L1000 Chem Pert Consensus Sigs (606)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (3)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (8)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (393)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (1)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (7)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (9)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
iloperidone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IRF8 Gene (Entity type)	0.008338929
SA-419172 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IRF8 Gene (Entity type)	0.010604905
SID11114027 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IRF8 Gene (Entity type)	0.008619693
PSH-023 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IRF8 Gene (Entity type)	-0.010957584
2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IRF8 Gene (Entity type)	-0.009668187
1-isopropyl-6-(6-(4-isopropylpiperazin-1-yl)pyridin-3-yl)-N-((6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl)-1H-indazole-4-carboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IRF8 Gene (Entity type)	-0.021582164
daphnetin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IRF8 Gene (Entity type)	0.008448529
Rhein Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IRF8 Gene (Entity type)	-0.03675086
HTS-11203SC Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IRF8 Gene (Entity type)	0.014736151
AG-494 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IRF8 Gene (Entity type)	-0.008985476