2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	INSM1 Gene (Entity type)	-0.010006191
2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DCK Gene (Entity type)	-0.010461077
2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	UGCG Gene (Entity type)	-0.010067453
2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Adenosine receptor A2b Protein (Entity type)	Ki
2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TBC1D31 Gene (Entity type)	0.0077570267
2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	neflamapimod Compound (Entity type)	0.1990272104740142
2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Adenosine receptor A3 Protein (Entity type)	Ki
2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EIF5A Gene (Entity type)	0.013565826
2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IRF8 Gene (Entity type)	-0.009668187
2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ENPP2 Gene (Entity type)	-0.008676355

2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
INSM1
Gene (Entity type)
-0.010006191

2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DCK
Gene (Entity type)
-0.010461077

2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
UGCG
Gene (Entity type)
-0.010067453

2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Adenosine receptor A2b
Protein (Entity type)
Ki

2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TBC1D31
Gene (Entity type)
0.0077570267

2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
neflamapimod
Compound (Entity type)
0.1990272104740142

2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Adenosine receptor A3
Protein (Entity type)
Ki

2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EIF5A
Gene (Entity type)
0.013565826

2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IRF8
Gene (Entity type)
-0.009668187

2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ENPP2
Gene (Entity type)
-0.008676355

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