LIF (Gene)

Description: LIF interleukin 6 family cytokine

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View LIF's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with LIF.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using LIF.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for LIF.

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Gene Sets (1071)

LINCS L1000 Chem Pert Consensus Sigs (626)

A gene set library provided by LINCS

LINCS L1000 CRISPR KO Consensus Sigs (420)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (22)

A gene set library provided by GTEx

GTEx Tissues V8 2023 (3)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
valyltryptophan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LIF Gene (Entity type)	0.010406303
fludrocortisone-acetate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LIF Gene (Entity type)	-0.01350372
SID11114146 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LIF Gene (Entity type)	0.0150407525
Macelignan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LIF Gene (Entity type)	0.04618705
cobimetinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LIF Gene (Entity type)	-0.00812996
8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LIF Gene (Entity type)	-0.013412353
Ulixertinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LIF Gene (Entity type)	-0.005855885
AZD-8330 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LIF Gene (Entity type)	-0.008414261
N4-(3-Bromo-phenyl)-N6-methyl-pyrido[3,4-d]pyrimidine-4,6-diamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LIF Gene (Entity type)	-0.011302019
TAK-733 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LIF Gene (Entity type)	-0.011272674