MCL1 (Gene)

Description: MCL1 apoptosis regulator, BCL2 family member

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View MCL1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with MCL1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using MCL1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for MCL1.

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Gene Sets (1530)

LINCS L1000 Chem Pert Consensus Sigs (636)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (15)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (12)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (862)

A gene set library provided by LINCS

GTEx Tissues V8 2023 (3)

A gene set library provided by GTEx

IDG Drug Targets 2022 (2)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
MW-A1-12 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MCL1 Gene (Entity type)	0.005430783
Clobetasol propionate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MCL1 Gene (Entity type)	0.009044832
Lenvatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MCL1 Gene (Entity type)	-0.004490704
SA-85901 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MCL1 Gene (Entity type)	-0.009501051
Rimexolone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MCL1 Gene (Entity type)	0.007703617
Iloprost Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MCL1 Gene (Entity type)	0.005341008
Olcegepant Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MCL1 Gene (Entity type)	-0.005887619
Istaroxime Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MCL1 Gene (Entity type)	0.004350782
[3-(5H-Dibenzo[a,d]cyclohepten-5-yl)-propyl]-methyl-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MCL1 Gene (Entity type)	-0.0035388903
Bisacodyl Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MCL1 Gene (Entity type)	0.0066333786