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Lenvatinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Lenvatinib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Lenvatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MEIS1 Gene (Entity type)	0.0046784244
	Lenvatinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Vascular endothelial growth factor receptor 3 Protein (Entity type)	IC50
	Lenvatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MCL1 Gene (Entity type)	-0.004490704
	Lenvatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IFI27 Gene (Entity type)	-0.005364366
	Lenvatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RAB11FIP1 Gene (Entity type)	-0.0058462583
	Lenvatinib Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Endometrial Carcinoma Disease or Phenotype (Entity type)
	Lenvatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TGFBI Gene (Entity type)	0.0055002393
	Lenvatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SERPINB5 Gene (Entity type)	-0.0040863743
	Lenvatinib Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Papillary thyroid carcinoma Disease or Phenotype (Entity type)
	Lenvatinib Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Renal Cell Carcinoma Disease or Phenotype (Entity type)

Lenvatinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MEIS1
Gene (Entity type)
0.0046784244

Lenvatinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Vascular endothelial growth factor receptor 3
Protein (Entity type)
IC50

Lenvatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MCL1
Gene (Entity type)
-0.004490704

Lenvatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IFI27
Gene (Entity type)
-0.005364366

Lenvatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RAB11FIP1
Gene (Entity type)
-0.0058462583

Lenvatinib
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Endometrial Carcinoma
Disease or Phenotype (Entity type)

Lenvatinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TGFBI
Gene (Entity type)
0.0055002393

Lenvatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SERPINB5
Gene (Entity type)
-0.0040863743

Lenvatinib
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Papillary thyroid carcinoma
Disease or Phenotype (Entity type)

Lenvatinib
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Renal Cell Carcinoma
Disease or Phenotype (Entity type)

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