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Istaroxime (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Istaroxime's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Istaroxime Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	COL3A1 Gene (Entity type)	-0.003925769
	Istaroxime Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PROM1 Gene (Entity type)	0.0050235926
	Istaroxime Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RHOB Gene (Entity type)	0.0039140987
	Istaroxime Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	dideoxyadenosine Compound (Entity type)	0.3461219370365143
	Istaroxime Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SNAP25 Gene (Entity type)	-0.0053872243
	Istaroxime Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FHL1 Gene (Entity type)	0.0038674045
	Istaroxime Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TFF1 Gene (Entity type)	0.004412245
	Istaroxime Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPP1 Gene (Entity type)	-0.004744803
	Istaroxime Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MCL1 Gene (Entity type)	0.004350782
	Istaroxime Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CASP10 Gene (Entity type)	-0.0047762278

Istaroxime
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
COL3A1
Gene (Entity type)
-0.003925769

Istaroxime
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PROM1
Gene (Entity type)
0.0050235926

Istaroxime
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RHOB
Gene (Entity type)
0.0039140987

Istaroxime
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
dideoxyadenosine
Compound (Entity type)
0.3461219370365143

Istaroxime
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SNAP25
Gene (Entity type)
-0.0053872243

Istaroxime
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FHL1
Gene (Entity type)
0.0038674045

Istaroxime
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TFF1
Gene (Entity type)
0.004412245

Istaroxime
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SPP1
Gene (Entity type)
-0.004744803

Istaroxime
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MCL1
Gene (Entity type)
0.004350782

Istaroxime
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CASP10
Gene (Entity type)
-0.0047762278

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