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S-ruxolitinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View S-ruxolitinib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	S-ruxolitinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRT13 Gene (Entity type)	-0.006215174
	isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	S-ruxolitinib Compound (Entity type)	0.3548267483711242
	S-ruxolitinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPINK1 Gene (Entity type)	-0.006120327
	S-ruxolitinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ADIRF Gene (Entity type)	-0.0071115172
	S-ruxolitinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ALDH1A2 Gene (Entity type)	0.005560821
	S-ruxolitinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CFH Gene (Entity type)	-0.006330876
	S-ruxolitinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ITGAE Gene (Entity type)	0.006087231
	S-ruxolitinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CALM3 Gene (Entity type)	0.006746048
	S-ruxolitinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CXCL14 Gene (Entity type)	-0.0058165514
	S-ruxolitinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SNAP25 Gene (Entity type)	0.005816961

S-ruxolitinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KRT13
Gene (Entity type)
-0.006215174

isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
S-ruxolitinib
Compound (Entity type)
0.3548267483711242

S-ruxolitinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SPINK1
Gene (Entity type)
-0.006120327

S-ruxolitinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ADIRF
Gene (Entity type)
-0.0071115172

S-ruxolitinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ALDH1A2
Gene (Entity type)
0.005560821

S-ruxolitinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CFH
Gene (Entity type)
-0.006330876

S-ruxolitinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ITGAE
Gene (Entity type)
0.006087231

S-ruxolitinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CALM3
Gene (Entity type)
0.006746048

S-ruxolitinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CXCL14
Gene (Entity type)
-0.0058165514

S-ruxolitinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SNAP25
Gene (Entity type)
0.005816961

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