S-ruxolitinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View S-ruxolitinib's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
S-ruxolitinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRT13 Gene (Entity type)	-0.006215174
isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	S-ruxolitinib Compound (Entity type)	0.3548267483711242
S-ruxolitinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPINK1 Gene (Entity type)	-0.006120327
S-ruxolitinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ADIRF Gene (Entity type)	-0.0071115172
S-ruxolitinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ALDH1A2 Gene (Entity type)	0.005560821
S-ruxolitinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CFH Gene (Entity type)	-0.006330876
S-ruxolitinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ITGAE Gene (Entity type)	0.006087231
S-ruxolitinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CALM3 Gene (Entity type)	0.006746048
S-ruxolitinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CXCL14 Gene (Entity type)	-0.0058165514
S-ruxolitinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SNAP25 Gene (Entity type)	0.005816961

S-ruxolitinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KRT13
Gene (Entity type)
-0.006215174

isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
S-ruxolitinib
Compound (Entity type)
0.3548267483711242

S-ruxolitinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SPINK1
Gene (Entity type)
-0.006120327

S-ruxolitinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ADIRF
Gene (Entity type)
-0.0071115172

S-ruxolitinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ALDH1A2
Gene (Entity type)
0.005560821

S-ruxolitinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CFH
Gene (Entity type)
-0.006330876

S-ruxolitinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ITGAE
Gene (Entity type)
0.006087231

S-ruxolitinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CALM3
Gene (Entity type)
0.006746048

S-ruxolitinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CXCL14
Gene (Entity type)
-0.0058165514

S-ruxolitinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SNAP25
Gene (Entity type)
0.005816961

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