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ITGAE (Gene)

Ensembl Gene ID: ENSG00000083457

Entrez Gene ID: 3682

Description: integrin subunit alpha E

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ITGAE's neighborhood in the knowledge graph.

Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with ITGAE.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using ITGAE.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for ITGAE.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ITGAE.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

This repository is under review for potential modification in compliance with Administration directives.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	SA-419050 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ITGAE Gene (Entity type)	-0.0173896
	MSX-122 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ITGAE Gene (Entity type)	-0.005764677
	SA-424170 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ITGAE Gene (Entity type)	0.012618215
	debrisoquin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ITGAE Gene (Entity type)	-0.035372
	L-690330 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ITGAE Gene (Entity type)	0.0035144722
	reboxetine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ITGAE Gene (Entity type)	0.003361144
	Metharbital Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ITGAE Gene (Entity type)	0.023711642
	N-(4-(2-Amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ITGAE Gene (Entity type)	0.0022620603
	SA-1460136 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ITGAE Gene (Entity type)	-0.022378126
	3-allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ITGAE Gene (Entity type)	0.015895339

SA-419050
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ITGAE
Gene (Entity type)
-0.0173896

MSX-122
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ITGAE
Gene (Entity type)
-0.005764677

SA-424170
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ITGAE
Gene (Entity type)
0.012618215

debrisoquin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ITGAE
Gene (Entity type)
-0.035372

L-690330
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ITGAE
Gene (Entity type)
0.0035144722

reboxetine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ITGAE
Gene (Entity type)
0.003361144

Metharbital
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ITGAE
Gene (Entity type)
0.023711642

N-(4-(2-Amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ITGAE
Gene (Entity type)
0.0022620603

SA-1460136
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ITGAE
Gene (Entity type)
-0.022378126

3-allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ITGAE
Gene (Entity type)
0.015895339

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