ITGAE (Gene)

Entrez Gene ID: 3682

Description: integrin subunit alpha E

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ITGAE's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with ITGAE.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using ITGAE.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for ITGAE.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ITGAE.

Gene Sets (1650)

LINCS L1000 Chem Pert Consensus Sigs (865)

A gene set library provided by LINCS

KOMP2 Mouse Phenotypes 2022 (6)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (778)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
SA-419050 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ITGAE Gene (Entity type)	-0.0173896
MSX-122 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ITGAE Gene (Entity type)	-0.005764677
SA-424170 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ITGAE Gene (Entity type)	0.012618215
debrisoquin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ITGAE Gene (Entity type)	-0.035372
L-690330 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ITGAE Gene (Entity type)	0.0035144722
reboxetine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ITGAE Gene (Entity type)	0.003361144
Metharbital Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ITGAE Gene (Entity type)	0.023711642
N-(4-(2-Amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ITGAE Gene (Entity type)	0.0022620603
SA-1460136 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ITGAE Gene (Entity type)	-0.022378126
3-allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ITGAE Gene (Entity type)	0.015895339

SA-419050
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ITGAE
Gene (Entity type)
-0.0173896

MSX-122
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ITGAE
Gene (Entity type)
-0.005764677

SA-424170
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ITGAE
Gene (Entity type)
0.012618215

debrisoquin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ITGAE
Gene (Entity type)
-0.035372

L-690330
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ITGAE
Gene (Entity type)
0.0035144722

reboxetine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ITGAE
Gene (Entity type)
0.003361144

Metharbital
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ITGAE
Gene (Entity type)
0.023711642

N-(4-(2-Amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ITGAE
Gene (Entity type)
0.0022620603

SA-1460136
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ITGAE
Gene (Entity type)
-0.022378126

3-allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ITGAE
Gene (Entity type)
0.015895339

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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.