[4-(2-piperidin-1-yl-ethoxy)-phenyl])-3-pyridin-4-yl-pyrrazolo[1,5-a]-pyrimidine (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View [4-(2-piperidin-1-yl-ethoxy)-phenyl])-3-pyridin-4-yl-pyrrazolo[1,5-a]-pyrimidine's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
[4-(2-piperidin-1-yl-ethoxy)-phenyl])-3-pyridin-4-yl-pyrrazolo[1,5-a]-pyrimidine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL14 Gene (Entity type)	0.011211659
Rebastinib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	[4-(2-piperidin-1-yl-ethoxy)-phenyl])-3-pyridin-4-yl-pyrrazolo[1,5-a]-pyrimidine Compound (Entity type)	0.2604720592498779
[4-(2-piperidin-1-yl-ethoxy)-phenyl])-3-pyridin-4-yl-pyrrazolo[1,5-a]-pyrimidine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MT1M Gene (Entity type)	0.008089444
[4-(2-piperidin-1-yl-ethoxy)-phenyl])-3-pyridin-4-yl-pyrrazolo[1,5-a]-pyrimidine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	JCHAIN Gene (Entity type)	-0.0077030617
[4-(2-piperidin-1-yl-ethoxy)-phenyl])-3-pyridin-4-yl-pyrrazolo[1,5-a]-pyrimidine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC2A10 Gene (Entity type)	-0.007177606
[4-(2-piperidin-1-yl-ethoxy)-phenyl])-3-pyridin-4-yl-pyrrazolo[1,5-a]-pyrimidine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CEBPA Gene (Entity type)	-0.010531649
[4-(2-piperidin-1-yl-ethoxy)-phenyl])-3-pyridin-4-yl-pyrrazolo[1,5-a]-pyrimidine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AMIGO2 Gene (Entity type)	-0.0090944385
[4-(2-piperidin-1-yl-ethoxy)-phenyl])-3-pyridin-4-yl-pyrrazolo[1,5-a]-pyrimidine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Vascular endothelial growth factor receptor 1 Protein (Entity type)	IC50
[4-(2-piperidin-1-yl-ethoxy)-phenyl])-3-pyridin-4-yl-pyrrazolo[1,5-a]-pyrimidine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RGCC Gene (Entity type)	0.009022153
[4-(2-piperidin-1-yl-ethoxy)-phenyl])-3-pyridin-4-yl-pyrrazolo[1,5-a]-pyrimidine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	THBS1 Gene (Entity type)	0.00764777

[4-(2-piperidin-1-yl-ethoxy)-phenyl])-3-pyridin-4-yl-pyrrazolo[1,5-a]-pyrimidine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CXCL14
Gene (Entity type)
0.011211659

Rebastinib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
[4-(2-piperidin-1-yl-ethoxy)-phenyl])-3-pyridin-4-yl-pyrrazolo[1,5-a]-pyrimidine
Compound (Entity type)
0.2604720592498779

[4-(2-piperidin-1-yl-ethoxy)-phenyl])-3-pyridin-4-yl-pyrrazolo[1,5-a]-pyrimidine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MT1M
Gene (Entity type)
0.008089444

[4-(2-piperidin-1-yl-ethoxy)-phenyl])-3-pyridin-4-yl-pyrrazolo[1,5-a]-pyrimidine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
JCHAIN
Gene (Entity type)
-0.0077030617

[4-(2-piperidin-1-yl-ethoxy)-phenyl])-3-pyridin-4-yl-pyrrazolo[1,5-a]-pyrimidine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLC2A10
Gene (Entity type)
-0.007177606

[4-(2-piperidin-1-yl-ethoxy)-phenyl])-3-pyridin-4-yl-pyrrazolo[1,5-a]-pyrimidine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CEBPA
Gene (Entity type)
-0.010531649

[4-(2-piperidin-1-yl-ethoxy)-phenyl])-3-pyridin-4-yl-pyrrazolo[1,5-a]-pyrimidine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AMIGO2
Gene (Entity type)
-0.0090944385

[4-(2-piperidin-1-yl-ethoxy)-phenyl])-3-pyridin-4-yl-pyrrazolo[1,5-a]-pyrimidine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Vascular endothelial growth factor receptor 1
Protein (Entity type)
IC50

[4-(2-piperidin-1-yl-ethoxy)-phenyl])-3-pyridin-4-yl-pyrrazolo[1,5-a]-pyrimidine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RGCC
Gene (Entity type)
0.009022153

[4-(2-piperidin-1-yl-ethoxy)-phenyl])-3-pyridin-4-yl-pyrrazolo[1,5-a]-pyrimidine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
THBS1
Gene (Entity type)
0.00764777

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