N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)-2-naphthamide (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)-2-naphthamide's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)-2-naphthamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SCD Gene (Entity type)	0.02516012
N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)-2-naphthamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ITGA6 Gene (Entity type)	-0.0060476037
N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)-2-naphthamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AMOTL2 Gene (Entity type)	-0.0073591038
N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)-2-naphthamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ID1 Gene (Entity type)	-0.006689077
N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)-2-naphthamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TFPI2 Gene (Entity type)	-0.008318059
N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)-2-naphthamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CA2 Gene (Entity type)	-0.0094248485
N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)-2-naphthamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Phospholipase D2 Protein (Entity type)	IC50
clomipramine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)-2-naphthamide Compound (Entity type)	0.7074404954910278
Fluoxetine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)-2-naphthamide Compound (Entity type)	0.5289295315742493
1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)-2-naphthamide Compound (Entity type)	0.4940305054187774