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OSI-027 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View OSI-027's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	OSI-027 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PCDH9 Gene (Entity type)	-0.0074127093
	OSI-027 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NT5E Gene (Entity type)	0.010359163
	OSI-027 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLAU Gene (Entity type)	0.0076671676
	OSI-027 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLAT Gene (Entity type)	0.0074029723
	OSI-027 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CHORDC1 Gene (Entity type)	-0.007836428
	OSI-027 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	0.8613381385803223
	OSI-027 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CIRBP Gene (Entity type)	0.007853471
	OSI-027 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one Compound (Entity type)	0.8064727187156677
	OSI-027 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SMAD3 Gene (Entity type)	0.01034224
	OSI-027 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TM4SF1 Gene (Entity type)	0.012960361

OSI-027
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PCDH9
Gene (Entity type)
-0.0074127093

OSI-027
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NT5E
Gene (Entity type)
0.010359163

OSI-027
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLAU
Gene (Entity type)
0.0076671676

OSI-027
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLAT
Gene (Entity type)
0.0074029723

OSI-027
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CHORDC1
Gene (Entity type)
-0.007836428

OSI-027
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
0.8613381385803223

OSI-027
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CIRBP
Gene (Entity type)
0.007853471

OSI-027
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one
Compound (Entity type)
0.8064727187156677

OSI-027
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SMAD3
Gene (Entity type)
0.01034224

OSI-027
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TM4SF1
Gene (Entity type)
0.012960361

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