PLAU (Gene)

Entrez Gene ID: 5328

Description: plasminogen activator, urokinase

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PLAU's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with PLAU.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PLAU.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PLAU.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PLAU.

Gene Sets (3983)

LINCS L1000 Chem Pert Consensus Sigs (827)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (8)

A gene set library provided by GlyGen

KOMP2 Mouse Phenotypes 2022 (4)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (691)

A gene set library provided by LINCS

rummageo gene perturbations (252)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (4)

A gene set library provided by GTEx

RummaGEO DrugPerturbations 2025 (574)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (1187)

A gene set library provided by LINCS

rummageo chemical perturbations (422)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (5)

A gene set library provided by GTEx

IDG Drug Targets 2022 (6)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
cleviprex Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLAU Gene (Entity type)	0.005430075
Ganetespib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PLAU Gene (Entity type)	-0.019569395
atropine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLAU Gene (Entity type)	0.014102123
Leucovorin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLAU Gene (Entity type)	0.022080002
SA-1921783 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLAU Gene (Entity type)	0.011782831
OSI-027 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLAU Gene (Entity type)	0.0076671676
CGP-37157 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLAU Gene (Entity type)	0.0047465684
SA-1920687 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PLAU Gene (Entity type)	-0.010889571
WZ-3146 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PLAU Gene (Entity type)	-0.011342007
AVA Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PLAU Gene (Entity type)	-0.0072888564

cleviprex
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLAU
Gene (Entity type)
0.005430075

Ganetespib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PLAU
Gene (Entity type)
-0.019569395

atropine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLAU
Gene (Entity type)
0.014102123

Leucovorin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLAU
Gene (Entity type)
0.022080002

SA-1921783
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLAU
Gene (Entity type)
0.011782831

OSI-027
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLAU
Gene (Entity type)
0.0076671676

CGP-37157
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLAU
Gene (Entity type)
0.0047465684

SA-1920687
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PLAU
Gene (Entity type)
-0.010889571

WZ-3146
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PLAU
Gene (Entity type)
-0.011342007

AVA
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PLAU
Gene (Entity type)
-0.0072888564

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Knowledge Graph Assertions

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.