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SAR-245408 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SAR-245408's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	SAR-245408 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FOSL1 Gene (Entity type)	0.0061967093
	SAR-245408 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MAFB Gene (Entity type)	-0.0048508625
	SAR-245408 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RGS2 Gene (Entity type)	-0.0044698357
	SAR-245408 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AKAP12 Gene (Entity type)	0.004394335
	SAR-245408 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ACTG2 Gene (Entity type)	0.004528668
	SAR-245408 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SFRP1 Gene (Entity type)	0.004227513
	SAR-245408 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LAGE3 Gene (Entity type)	0.004096066
	SAR-245408 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide Compound (Entity type)	0.35151407122612
	SAR-245408 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(E/Z)-3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one Compound (Entity type)	0.354787141084671
	SAR-245408 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FOXO4 Gene (Entity type)	-0.0040226886

SAR-245408
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FOSL1
Gene (Entity type)
0.0061967093

SAR-245408
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MAFB
Gene (Entity type)
-0.0048508625

SAR-245408
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RGS2
Gene (Entity type)
-0.0044698357

SAR-245408
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AKAP12
Gene (Entity type)
0.004394335

SAR-245408
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ACTG2
Gene (Entity type)
0.004528668

SAR-245408
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SFRP1
Gene (Entity type)
0.004227513

SAR-245408
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LAGE3
Gene (Entity type)
0.004096066

SAR-245408
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide
Compound (Entity type)
0.35151407122612

SAR-245408
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(E/Z)-3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one
Compound (Entity type)
0.354787141084671

SAR-245408
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FOXO4
Gene (Entity type)
-0.0040226886

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