N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EREG Gene (Entity type)	0.004874505
7,10-dimethyl-2,4-dioxo-2,3,4,10-tetrahydrobenzo[g]pteridine-8-carbaldehyde Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide Compound (Entity type)	0.2350838482379913
N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DUSP6 Gene (Entity type)	0.004927039
N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EGR1 Gene (Entity type)	0.0051072813
N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Dual specificity mitogen-activated protein kinase kinase 5 Protein (Entity type)	Kd
N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NFATC3 Gene (Entity type)	-0.0046465904
SID103905642 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide Compound (Entity type)	0.5339112281799316
N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMT1A Gene (Entity type)	-0.0038253984
N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HSPB8 Gene (Entity type)	-0.0052081635
SAR-245408 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide Compound (Entity type)	0.35151407122612

N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EREG
Gene (Entity type)
0.004874505

7,10-dimethyl-2,4-dioxo-2,3,4,10-tetrahydrobenzo[g]pteridine-8-carbaldehyde
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide
Compound (Entity type)
0.2350838482379913

N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DUSP6
Gene (Entity type)
0.004927039

N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EGR1
Gene (Entity type)
0.0051072813

N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Dual specificity mitogen-activated protein kinase kinase 5
Protein (Entity type)
Kd

N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NFATC3
Gene (Entity type)
-0.0046465904

SID103905642
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide
Compound (Entity type)
0.5339112281799316

N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TMT1A
Gene (Entity type)
-0.0038253984

N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HSPB8
Gene (Entity type)
-0.0052081635

SAR-245408
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide
Compound (Entity type)
0.35151407122612

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.