3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one (WEB 2086) (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one (WEB 2086)'s neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one (WEB 2086) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PACSIN2 Gene (Entity type)	0.0034850577
3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one (WEB 2086) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RAB11FIP1 Gene (Entity type)	-0.004076397
Bicalutamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one (WEB 2086) Compound (Entity type)	0.559566855430603
3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one (WEB 2086) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CREB1 Gene (Entity type)	0.0036761619
3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one (WEB 2086) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLOD2 Gene (Entity type)	0.004313498
3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one (WEB 2086) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ANXA3 Gene (Entity type)	0.0035588485
3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one (WEB 2086) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMEM176A Gene (Entity type)	-0.004404886
3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one (WEB 2086) Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	dapivirine Compound (Entity type)	0.4449845254421234
3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one (WEB 2086) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TUBB2B Gene (Entity type)	-0.004972937
3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one (WEB 2086) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MAGEA12 Gene (Entity type)	0.0036781656

3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one (WEB 2086)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PACSIN2
Gene (Entity type)
0.0034850577

3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one (WEB 2086)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RAB11FIP1
Gene (Entity type)
-0.004076397

Bicalutamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one (WEB 2086)
Compound (Entity type)
0.559566855430603

3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one (WEB 2086)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CREB1
Gene (Entity type)
0.0036761619

3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one (WEB 2086)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLOD2
Gene (Entity type)
0.004313498

3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one (WEB 2086)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ANXA3
Gene (Entity type)
0.0035588485

3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one (WEB 2086)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TMEM176A
Gene (Entity type)
-0.004404886

3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one (WEB 2086)
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
dapivirine
Compound (Entity type)
0.4449845254421234

3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one (WEB 2086)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TUBB2B
Gene (Entity type)
-0.004972937

3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one (WEB 2086)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MAGEA12
Gene (Entity type)
0.0036781656

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