CREB1 (Gene)

Entrez Gene ID: 1385

Description: cAMP responsive element binding protein 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CREB1's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CREB1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CREB1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CREB1.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CREB1.

Gene Sets (2078)

LINCS L1000 Chem Pert Consensus Sigs (581)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (1)

A gene set library provided by GlyGen

LINCS L1000 CRISPR KO Consensus Sigs (311)

A gene set library provided by LINCS

rummageo gene perturbations (82)

A gene set library provided by LINCS

RummaGEO DrugPerturbations 2025 (136)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (879)

A gene set library provided by LINCS

rummageo chemical perturbations (86)

A gene set library provided by LINCS

Knowledge Graph Assertions

Source	Relation	Target	Evidence
SID11113608 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CREB1 Gene (Entity type)	-0.007689736
ampalex Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CREB1 Gene (Entity type)	0.0036226567
STK-222600 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CREB1 Gene (Entity type)	0.004624298
Y-27152 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CREB1 Gene (Entity type)	-0.0042214165
Myricetin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CREB1 Gene (Entity type)	0.00832818
Closantel Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CREB1 Gene (Entity type)	-0.0049952925
7-methyl-2-morpholino-9-(1-(phenylamino)ethyl)-4H-pyrido[1,2-a]pyrimidin-4-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CREB1 Gene (Entity type)	-0.0038752286
Telatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CREB1 Gene (Entity type)	-0.0030660387
ST-022313 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CREB1 Gene (Entity type)	0.0117649855
Alagebrium Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CREB1 Gene (Entity type)	0.006230078

SID11113608
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CREB1
Gene (Entity type)
-0.007689736

ampalex
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CREB1
Gene (Entity type)
0.0036226567

STK-222600
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CREB1
Gene (Entity type)
0.004624298

Y-27152
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CREB1
Gene (Entity type)
-0.0042214165

Myricetin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CREB1
Gene (Entity type)
0.00832818

Closantel
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CREB1
Gene (Entity type)
-0.0049952925

7-methyl-2-morpholino-9-(1-(phenylamino)ethyl)-4H-pyrido[1,2-a]pyrimidin-4-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CREB1
Gene (Entity type)
-0.0038752286

Telatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CREB1
Gene (Entity type)
-0.0030660387

ST-022313
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CREB1
Gene (Entity type)
0.0117649855

Alagebrium
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CREB1
Gene (Entity type)
0.006230078

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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.