N-{5-methoxy-6-methyl-18-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl}-N-methylbenzamide (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View N-{5-methoxy-6-methyl-18-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl}-N-methylbenzamide's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-{5-methoxy-6-methyl-18-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl}-N-methylbenzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MMP7 Gene (Entity type)	0.003977779
N-{5-methoxy-6-methyl-18-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl}-N-methylbenzamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	brigatinib Compound (Entity type)	0.4528584778308868
N-{5-methoxy-6-methyl-18-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl}-N-methylbenzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CASP2 Gene (Entity type)	-0.004240978
N-{5-methoxy-6-methyl-18-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl}-N-methylbenzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RPS4Y1 Gene (Entity type)	-0.0035310672
N-{5-methoxy-6-methyl-18-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl}-N-methylbenzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DHRS2 Gene (Entity type)	-0.0042326055
N-{5-methoxy-6-methyl-18-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl}-N-methylbenzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NNMT Gene (Entity type)	0.0042702258
N-{5-methoxy-6-methyl-18-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl}-N-methylbenzamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Epidermal growth factor receptor Protein (Entity type)	Kd
N-{5-methoxy-6-methyl-18-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl}-N-methylbenzamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Calcium/calmodulin-dependent protein kinase type II subunit alpha Protein (Entity type)	Kd
N-{5-methoxy-6-methyl-18-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl}-N-methylbenzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FABP4 Gene (Entity type)	0.005979014
N-{5-methoxy-6-methyl-18-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl}-N-methylbenzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TACSTD2 Gene (Entity type)	-0.0038534126

N-{5-methoxy-6-methyl-18-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl}-N-methylbenzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MMP7
Gene (Entity type)
0.003977779

N-{5-methoxy-6-methyl-18-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl}-N-methylbenzamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
brigatinib
Compound (Entity type)
0.4528584778308868

N-{5-methoxy-6-methyl-18-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl}-N-methylbenzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CASP2
Gene (Entity type)
-0.004240978

N-{5-methoxy-6-methyl-18-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl}-N-methylbenzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RPS4Y1
Gene (Entity type)
-0.0035310672

N-{5-methoxy-6-methyl-18-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl}-N-methylbenzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DHRS2
Gene (Entity type)
-0.0042326055

N-{5-methoxy-6-methyl-18-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl}-N-methylbenzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NNMT
Gene (Entity type)
0.0042702258

N-{5-methoxy-6-methyl-18-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl}-N-methylbenzamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Epidermal growth factor receptor
Protein (Entity type)
Kd

N-{5-methoxy-6-methyl-18-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl}-N-methylbenzamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Calcium/calmodulin-dependent protein kinase type II subunit alpha
Protein (Entity type)
Kd

N-{5-methoxy-6-methyl-18-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl}-N-methylbenzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FABP4
Gene (Entity type)
0.005979014

N-{5-methoxy-6-methyl-18-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl}-N-methylbenzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TACSTD2
Gene (Entity type)
-0.0038534126

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.