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brigatinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View brigatinib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	brigatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CTSZ Gene (Entity type)	-0.004379125
	brigatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LMO4 Gene (Entity type)	-0.004897582
	brigatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DKK1 Gene (Entity type)	-0.0058944924
	N-{5-methoxy-6-methyl-18-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl}-N-methylbenzamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	brigatinib Compound (Entity type)	0.4528584778308868
	brigatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FOSL1 Gene (Entity type)	-0.006563685
	brigatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AQP3 Gene (Entity type)	0.0066040205
	brigatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DLD Gene (Entity type)	-0.0044243364
	brigatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AZGP1 Gene (Entity type)	0.0067026713
	brigatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ESR1 Gene (Entity type)	0.0058184797
	brigatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL14 Gene (Entity type)	0.0054253815

brigatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CTSZ
Gene (Entity type)
-0.004379125

brigatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LMO4
Gene (Entity type)
-0.004897582

brigatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DKK1
Gene (Entity type)
-0.0058944924

N-{5-methoxy-6-methyl-18-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl}-N-methylbenzamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
brigatinib
Compound (Entity type)
0.4528584778308868

brigatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FOSL1
Gene (Entity type)
-0.006563685

brigatinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AQP3
Gene (Entity type)
0.0066040205

brigatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DLD
Gene (Entity type)
-0.0044243364

brigatinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AZGP1
Gene (Entity type)
0.0067026713

brigatinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ESR1
Gene (Entity type)
0.0058184797

brigatinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CXCL14
Gene (Entity type)
0.0054253815

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