NNMT (Gene)

Entrez Gene ID: 4837

Description: nicotinamide N-methyltransferase

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View NNMT's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with NNMT.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using NNMT.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for NNMT.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with NNMT.

Gene Sets (3096)

LINCS L1000 Chem Pert Consensus Sigs (1620)

A gene set library provided by LINCS

KOMP2 Mouse Phenotypes 2022 (8)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (1463)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (2)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

IDG Drug Targets 2022 (2)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
efaproxiral Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NNMT Gene (Entity type)	0.0034368783
NNMT Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	niacinamide Metabolite (Entity type)
Alectinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NNMT Gene (Entity type)	-0.004575828
1-phenylbiguanide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NNMT Gene (Entity type)	0.0128378915
NNMT Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	S-Adenosylhomocysteine Metabolite (Entity type)
zonisamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NNMT Gene (Entity type)	-0.003650232
2-methyl-6-(phenylethynyl)pyridine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NNMT Gene (Entity type)	-0.0053342194
SID11114164 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NNMT Gene (Entity type)	0.009213439
isogedunin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NNMT Gene (Entity type)	0.011091281
nikkomycin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NNMT Gene (Entity type)	0.011022814

efaproxiral
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NNMT
Gene (Entity type)
0.0034368783

NNMT
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
niacinamide
Metabolite (Entity type)

Alectinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NNMT
Gene (Entity type)
-0.004575828

1-phenylbiguanide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NNMT
Gene (Entity type)
0.0128378915

NNMT
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
S-Adenosylhomocysteine
Metabolite (Entity type)

zonisamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NNMT
Gene (Entity type)
-0.003650232

2-methyl-6-(phenylethynyl)pyridine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NNMT
Gene (Entity type)
-0.0053342194

SID11114164
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NNMT
Gene (Entity type)
0.009213439

isogedunin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NNMT
Gene (Entity type)
0.011091281

nikkomycin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NNMT
Gene (Entity type)
0.011022814

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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.