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Saracatinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Saracatinib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Saracatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TPM2 Gene (Entity type)	-0.0036213365
	Saracatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CYP4B1 Gene (Entity type)	0.0044296677
	Saracatinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Tyrosine-protein kinase Lck Protein (Entity type)	IC50
	Saracatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GPNMB Gene (Entity type)	0.0045916466
	Saracatinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Tyrosine-protein kinase ABL1 Protein (Entity type)	IC50
	Saracatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PALLD Gene (Entity type)	-0.003979568
	Saracatinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Activin receptor type-1 Protein (Entity type)	Kd
	Saracatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SCD Gene (Entity type)	0.0063223517
	Saracatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GLIPR1 Gene (Entity type)	-0.004398635
	P505-15 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Saracatinib Compound (Entity type)	0.2535000145435333

Saracatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TPM2
Gene (Entity type)
-0.0036213365

Saracatinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CYP4B1
Gene (Entity type)
0.0044296677

Saracatinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Tyrosine-protein kinase Lck
Protein (Entity type)
IC50

Saracatinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GPNMB
Gene (Entity type)
0.0045916466

Saracatinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Tyrosine-protein kinase ABL1
Protein (Entity type)
IC50

Saracatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PALLD
Gene (Entity type)
-0.003979568

Saracatinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Activin receptor type-1
Protein (Entity type)
Kd

Saracatinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SCD
Gene (Entity type)
0.0063223517

Saracatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GLIPR1
Gene (Entity type)
-0.004398635

P505-15
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Saracatinib
Compound (Entity type)
0.2535000145435333

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