N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL8 Gene (Entity type)	0.007402546
N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CYP51A1 Gene (Entity type)	0.00589265
N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine Compound (Entity type)	0.5041531324386597
N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SC5D Gene (Entity type)	0.004579495
N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Tetrandrine Compound (Entity type)	0.466329276561737
N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FASN Gene (Entity type)	0.004808963
N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ASNS Gene (Entity type)	-0.004847049
N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Obatoclax Compound (Entity type)	0.4954232573509216
N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GSTM3 Gene (Entity type)	-0.003783899
N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IDI1 Gene (Entity type)	0.007814547

N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CXCL8
Gene (Entity type)
0.007402546

N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CYP51A1
Gene (Entity type)
0.00589265

N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
Compound (Entity type)
0.5041531324386597

N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SC5D
Gene (Entity type)
0.004579495

N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Tetrandrine
Compound (Entity type)
0.466329276561737

N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FASN
Gene (Entity type)
0.004808963

N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ASNS
Gene (Entity type)
-0.004847049

N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Obatoclax
Compound (Entity type)
0.4954232573509216

N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GSTM3
Gene (Entity type)
-0.003783899

N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IDI1
Gene (Entity type)
0.007814547

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